ACE Prevention was a large, 5-year study funded by the National Health and Medical Research Council (NHMRC) and jointly led by Professor Theo Vos of the Centre for Burden of Disease and Cost-Effectiveness at The University of Queensland and Professor Rob Carter of the Deakin Health Economics Unit at Deakin University. The final report was presented on 8 September 2010.


The overall aim of this project was to provide a comprehensive analysis of the comparative cost-effectiveness of preventive intervention options addressing the non-communicable disease burden in Australia, with a specific focus on Indigenous Australians.


ACE Prevention is the most comprehensive evaluation of health prevention measures ever conducted world-wide, involving input from 130 top health experts. The research team assessed 123 illness prevention measures to identify those which will prevent the most illness and premature deaths and those that are best value for money. For comparison purposes 27 treatment interventions were included. To ensure maximum comparability between the results for different interventions, an ACE Prevention Economic Protocol [600kB] was developed.


Download the ACE Prevention final report [3MB] 


The specific objectives of ACE Prevention were to:

1. assess the relative cost-effectiveness of a comprehensive set of preventive interventions for non-communicable disease in Australia, together with a selected set of comparator care/cure interventions, as a critical input to resource allocation decisions in the health sector;

2. recommend a ‘menu’ of cost-effective interventions from which policy makers can choose an optimal mix of preventive interventions for non-communicable disease control within the constraints of current budgets allocated to prevention, and alternative scenarios of budgetary provision;

3. evaluate the impact on costs and outcomes separately for each of the interventions and combinations thereof if directed at Indigenous Australians; and

4. strengthen the use of evidence in health priority setting in by increasing the capacity among key stakeholders to more effectively incorporate research findings into policy and programme debates taking into account issues of equity, acceptability to stakeholders and feasibility of implementation.


The final report [3MB] provides a comprehensive overview of the findings of ACE Prevention. For results on specific topics, please see the listing below.


ACE Prevention section

ACE Prevention methods

Methods used on the ACE Prevention project

ACE Prevention presentation

Presentations on the project's findings

ACE Prevention results

Full list of results from the ACE Prevention project

ACE Prevention: Alcohol

The project's findings and publications regarding alcohol consumption

ACE Prevention: Blood pressure and cholesterol lowering

Findings and publications regarding blood pressure and cholesterol lowering

ACE Prevention: Body mass

This page details the project's findings on body mass and obesity

ACE Prevention: Bone mineral density

Findings and publications regarding bone mineral density

ACE Prevention: Cervical cancer

Details of our findings regarding cervical cancer

ACE Prevention: Chronic kidney disease

Our findings regarding chronic kidney disease

ACE Prevention: Fruits and vegetables

Details regarding the project's findings regarding fruit and vegetable consumption

ACE Prevention: Illicit drugs

Information regarding the project's findings and publications on illicit drugs

ACE Prevention: Indigenous results

Findings and publications regarding Indigenous health

ACE Prevention: Influenza

The project's findings and publications regarding influenza

ACE Prevention: Mental health

Details of the project's findings on mental health

ACE Prevention: Multi component

Findings and publications from this aspect of the project

ACE Prevention: Oral health

The project's findings and publications around oral health

ACE Prevention: Osteoarthritis

The project's findings and publications on osteoarthritis

ACE Prevention: Physical activity

The project's findings and publications regarding physical activity

ACE Prevention: Pre-diabetes

Details of our findings regarding pre-diabetes

ACE Prevention: Salt

This pages includes the project's findings regarding salt consumption

ACE Prevention: Shingles

The project's findings and publications regarding shingles

ACE Prevention: Skin cancer

Details of the project's findings regarding skin cancer

ACE Prevention: Vision loss

Papers summarising our findings regarding vision loss

On this site