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ACE Prevention
Download the ACE Prevention final report [3MB]
ACE Prevention is a large, 5-year study that was funded by the National Health and Medical Research Council (NHMRC) and jointly led by professor Theo Vos of the Centre for Burden of Disease and Cost-Effectiveness at the University of Queensland and professor Rob Carter of the Deakin Health Economics Unit at Deakin University. The final report was presented on 8 September 2010.
The final report [3MB] provides a comprehensive overview of the findings of ACE Prevention. For results on specific topics, please see the listing below.
The specific objectives of ACE Prevention were to:
1. assess the relative cost-effectiveness of a comprehensive set of preventive interventions for non-communicable disease in Australia, together with a selected set of comparator care/cure interventions, as a critical input to resource allocation decisions in the health sector;
2. recommend a ‘menu’ of cost-effective interventions from which policy makers can choose an optimal mix of preventive interventions for non-communicable disease control within the constraints of current budgets allocated to prevention, and alternative scenarios of budgetary provision;
3. evaluate the impact on costs and outcomes separately for each of the interventions and combinations thereof if directed at Indigenous Australians; and
4. strengthen the use of evidence in health priority setting in by increasing the capacity among key stakeholders to more effectively incorporate research findings into policy and programme debates taking into account issues of equity, acceptability to stakeholders and feasibility of implementation.
To ensure maximum comparability between the results for different interventions, an ACE Prevention Economic Protocol [600kB] was developed.
ACE Prevention final report
Read the project's final report.
The final report can be read here.
ACE Prevention methods
Methods used on the ACE Prevention project.
ACE Prevention: Alcohol
The project's findings and publications regarding alcohol consumption.
Cobiac LJ, Vos T, Doran C, Wallace A. Cost-effectiveness of interventions to prevent alcohol-related disease and injury in Australia. Addiction 2009;104:1646-1655.
ACE Prevention: Anal cancer
Details of findings regarding anal cancer.
Peer-reviewed publication in preparation.
ACE Prevention: Asthma
This content is currently being prepared.
Content to come.
ACE Prevention: Blood pressure and cholestoral lowering
Findings and publications regarding blood pressure and cholestoral lowering.
Cobiac LJ, Magnus A, Lim S, Barendregt JJ, Carter R, Vos T. Which interventions offer best value for money in primary prevention of cardiovascular disease? PLoS One. 2012;7(7):e41842. Epub 2012 Jul 23.
Cobiac LJ, Magnus A, Barendregt JJ, Carter R, Vos T. Improving the cost-effectiveness of cardiovascular disease prevention in Australia: a modelling study. BMC Public Health. 2012 Jun 1;12(1):39
Pamphlet 3: Blood pressure and cholesterol lowering
ACE Prevention: Body mass
This page details the project's findings on body mass and obesity.
Forster M, Veerman JL, Barendregt JJ, Vos T. Cost-effectiveness of diet and exercise interventions to reduce overweight and obesity. International Journal of Obesity, advance online publication 11 January 2011; doi: 10.1038/ijo.2010.246.
ACE Prevention: Bone mineral density
Findings and publications regarding bone mineral density.
Peer-reviewed publications in preparation
ACE Prevention: Breast cancer
This content is currently being prepared.
Content to come.
ACE Prevention: Cervical cancer
Details of our findings regarding cervical cancer.
Shih S, Mihalopoulos C, Carter R. Costing on cervical cancer screening and management of screen detected abnormalities based on NHMRC guidelines. In preparation.
Shih S, Barendregt JJ, Mihalopoulos C, Carter R, Vos T. Options for change of cervical cancer screening strategy: cost-effectiveness results from a micro-simulation model. In preparation.
Shih S, Vos T, Magnus A, Carter R. Directions of Australian cervical screening policy in the context of HPV vaccination. In preparation.
ACE Prevention: Chronic kidney disease
Our findings regarding chronic kidney disease.
ACE Prevention: CVD treatment
Findings and publications regarding the treatment of cardiovascular disease.
Peer-reviewed publications on rehabilitation, revascularisation, drug-eluting stents and PCI versus thrombolysis are in preparation.
ACE Prevention: Diarrhoea
This content is currently being prepared.
Content to come.
ACE Prevention: Fruits and vegetables
Details regarding the project's findings regarding fruit and vegetable consumption.
Pamphlet 7: Fruit and vegetables
ACE Prevention: Hepatitis B
Details of our findings re hepatitis B.
Peer-reviewed publication in preparation.
ACE Prevention: HIV
The project's findings and publications regarding HIV.
ACE Prevention: Illicit drugs
Information regarding the project's findings and publications on illicit drugs.
Tay-Teo K, Bulfone L, Carter R, Doran C, Hall W. Modelling the public health consequences of cannabis use in Australia. In preparation.
ACE Prevention: Indigenous results
Findings and publications regarding Indigenous health.
Ong K, Kelaher M, Anderson I, Carter R. A cost-based equity weight for use in the economic evaluation of primary health care interventions: case study of the Australian Indigenous population.International Journal for Equity in Health 2009, 8:34
ACE Prevention: Influenza
The project's findings and publications regarding influenza.
Mogasale V, Barendregt JJ. Cost-effectiveness of influenza vaccination of people aged 50-64 year in Australia: results are inconclusive. ANZPH, 2011;35 (2):180-6.
(With comments in a letter from Newall & Scuffham and response from Mogasale & Barendregt)
ACE Prevention: Mental health
Details of the project's findings on mental health.
ACE Prevention: Multi component
Findings and publications from this aspect of the project.
Cobiac LJ, Vos T, Veerman JL. Cost-effectiveness of Weight Watchers and the Lighten Up to a Healthy Lifestyle program. Aust N Z J Public Health 2010;34(3):240–247.
ACE Prevention: Oral health
The project's findings and publications around oral health.
Cobiac LJ, Vos T. Cost-effectiveness of extending the coverage of water supply fluoridation for the prevention of dental caries in Australia. Community Dent Oral Epidemiol 2012. Epub online: 27 MAR 2012
ACE Prevention: Osteoarthritis
The project's findings and publications on osteoarthritis.
Higashi H, Barendregt JJ (2011) Cost-Effectiveness of Total Hip and Knee Replacements for the Australian Population with Osteoarthritis: Discrete-Event Simulation Model. PLoS ONE 6(9): e25403. doi:10.1371/journal.pone.0025403.
Briefing paper Osteoarthritis hip and knee
Briefing paper Osteoarthritis hip and knee - appendix
ACE Prevention: Peptic ulcer disease
This content is currently being prepared.
Content to come
ACE Prevention: Physical activity
The project's findings and publications regarding physical activity.
Cobiac LJ, Vos T, Barendregt JJ. Cost-effectiveness of interventions to promote physical activity: a modelling study. PLoS Med 2009;6:e1000110
ACE Prevention: Prediabetes
Details of our findings re prediabetes.
ACE Prevention: Prostate cancer
Details of the project's findings regarding prostate cancer.
Pamphlet 5: Cervical cancer screening, SunSmart and PSA screening
ACE Prevention: Salt
This pages includes the project's findings regarding salt consumption.
ACE Prevention: Shingles
The project's findings and publications regarding shingles.
ACE Prevention: Skin cancer
Details of the project's findings regarding skin cancer.
ACE Prevention: Tobacco
This content is currently being prepared.
Peer-reviewed publications in preparation.
Pamphlet 17: Tobacco - In preparation
ACE Prevention: Vision loss
Papers summarising our findings regarding vision loss.
