Download the ACE Prevention final report [3MB]

 


ACE Prevention is a large, 5-year study that was funded by the National Health and Medical Research Council (NHMRC) and jointly led by professor Theo Vos of the Centre for Burden of Disease and Cost-Effectiveness at the University of Queensland and professor Rob Carter of the Deakin Health Economics Unit at Deakin University. The final report was presented on 8 September 2010.

The overall aim of this project was to provide a comprehensive analysis of the comparative cost-effectiveness of preventive intervention options addressing the non-communicable disease burden in Australia, with a specific focus on Indigenous Australians.
 
ACE Prevention is the most comprehensive evaluation of health prevention measures ever conducted world-wide, involving input from 130 top health experts. The research team assessed 123 illness prevention measures to identify those which will prevent the most illness and premature deaths and those that are best value for money. For comparison purposes 27 treatment interventions were included.

The final report [3MB] provides a comprehensive overview of the findings of ACE Prevention. For results on specific topics, please see the listing below.


The specific objectives of ACE Prevention were to:

1. assess the relative cost-effectiveness of a comprehensive set of preventive interventions for non-communicable disease in Australia, together with a selected set of comparator care/cure interventions, as a critical input to resource allocation decisions in the health sector;

2. recommend a ‘menu’ of cost-effective interventions from which policy makers can choose an optimal mix of preventive interventions for non-communicable disease control within the constraints of current budgets allocated to prevention, and alternative scenarios of budgetary provision;

3. evaluate the impact on costs and outcomes separately for each of the interventions and combinations thereof if directed at Indigenous Australians; and

4. strengthen the use of evidence in health priority setting in by increasing the capacity among key stakeholders to more effectively incorporate research findings into policy and programme debates taking into account issues of equity, acceptability to stakeholders and feasibility of implementation.

To ensure maximum comparability between the results for different interventions, an ACE Prevention Economic Protocol [600kB] was developed.

ACE Prevention final report

ACE Prevention final report

Read the project's final report.

The final report can be read here.

ACE Prevention methods

ACE Prevention methods

Methods used on the ACE Prevention project.

ACE Prevention: Alcohol

ACE Prevention: Alcohol

The project's findings and publications regarding alcohol consumption.

 Cobiac LJ, Vos T, Doran C, Wallace A. Cost-effectiveness of interventions to prevent alcohol-related disease and injury in Australia. Addiction 2009;104:1646-1655.

Byrnes J, Cobiac L, Doran C, Vos T, Shakeshaft A. The cost-effectiveness of volumetric alcohol taxation in Australia. Medical Journal of Australia 2010;192:439-443.
 
Hall W, Wallace A, Cobiac L, Doran C, Vos T. How can we reduce alcohol-related road crashes among young Australians? Medical Journal of Australia 2010;192:464-466.
 
Doran C, Hall W, Shakeshaft A, Vos T, Cobiac L. Alcohol policy reform in Australia: what can we learn from the evidence? Medical Journal of Australia 2010;192: 468-470.
 
Doran C, Cobiac L, Byrnes J, Vos T (2010) Alcohol taxation and distribution of gains. National Drug and Alcohol Research Centre, University of New South Wales; Centre for Burden of Disease and Cost-Effectiveness, The University of Queensland; VicHealth; Public Health Association of Australia.

Pamphlet 2: Alcohol

ACE Prevention: Anal cancer

ACE Prevention: Anal cancer

Details of findings regarding anal cancer.

Peer-reviewed publication in preparation.

ACE Prevention: Asthma

ACE Prevention: Asthma

This content is currently being prepared.

Content to come.  

ACE Prevention: Blood pressure and cholestoral lowering

ACE Prevention: Blood pressure and cholestoral lowering

Findings and publications regarding blood pressure and cholestoral lowering.

Cobiac LJ, Magnus A, Lim S, Barendregt JJ, Carter R, Vos T. Which interventions offer best value for money in primary prevention of cardiovascular disease? PLoS One. 2012;7(7):e41842. Epub 2012 Jul 23.

Cobiac LJ, Magnus A, Barendregt JJ, Carter R, Vos T. Improving the cost-effectiveness of cardiovascular disease prevention in Australia: a modelling study. BMC Public Health. 2012 Jun 1;12(1):39

 

Pamphlet 3Blood pressure and cholesterol lowering

 

ACE Prevention: Body mass

ACE Prevention: Body mass

This page details the project's findings on body mass and obesity.

Forster M, Veerman JL, Barendregt JJ, Vos T. Cost-effectiveness of diet and exercise interventions to reduce overweight and obesity. International Journal of Obesity, advance online publication 11 January 2011; doi: 10.1038/ijo.2010.246.

Veerman JL, Forster M, Barendregt JJ, Vos T. Cost-effectiveness of pharmacological interventions to reduce overweight and obesity. PLoS ONE 6(10): e26051. 27 Oct 2011. doi:10.1371/journal.pone.0026051
 
Sacks G, Veerman JL, Moody M, Swinburn B. ‘Traffic-light’ nutrition labelling and ‘junk-food’ tax: a modelled comparison of cost-effectiveness for obesity prevention. International Journal of Obesity, advance online publication 16 November 2010; doi: 10.1038/ijo.2010.228.
 
Lee YY, Veerman JL, Barendregt JJ. The Cost-Effectiveness of Laparoscopic Adjustable Gastric Banding in the Morbidly Obese Adult Population of Australia. PLoS ONE 8(5): e64965. doi:10.1371/journal.pone.0064965

 

ACE Prevention: Bone mineral density

ACE Prevention: Bone mineral density

Findings and publications regarding bone mineral density.

ACE Prevention: Breast cancer

ACE Prevention: Breast cancer

This content is currently being prepared.

Content to come. 

ACE Prevention: Cervical cancer

ACE Prevention: Cervical cancer

Details of our findings regarding cervical cancer.

Shih S, Mihalopoulos C, Carter R. Costing on cervical cancer screening and management of screen detected abnormalities based on NHMRC guidelines. In preparation.

Shih S, Barendregt JJ, Mihalopoulos C, Carter R, Vos T. Options for change of cervical cancer screening strategy: cost-effectiveness results from a micro-simulation model. In preparation.

Shih S, Vos T, Magnus A, Carter R. Directions of Australian cervical screening policy in the context of HPV vaccination. In preparation.

Briefing paper Cervical cancer (not yet publicly available; work for PhD thesis)
 

 

ACE Prevention: Chronic kidney disease

ACE Prevention: Chronic kidney disease

Our findings regarding chronic kidney disease.

ACE Prevention: CVD treatment

ACE Prevention: CVD treatment

Findings and publications regarding the treatment of cardiovascular disease.

 Peer-reviewed publications on rehabilitation, revascularisation, drug-eluting stents and PCI versus thrombolysis are in preparation.

ACE Prevention: Diarrhoea

ACE Prevention: Diarrhoea

This content is currently being prepared.

Content to come.

 

 

ACE Prevention: Fruits and vegetables

ACE Prevention: Fruits and vegetables

Details regarding the project's findings regarding fruit and vegetable consumption.

Cobiac LJ, Vos T, Veerman JL. Cost-effectiveness of interventions to promote fruit and vegetable consumption. PLoS ONE 5(11): e14148. doi:10.1371/journal.pone.0014148.
 

Pamphlet 7: Fruit and vegetables

 

ACE Prevention: Hepatitis B

ACE Prevention: Hepatitis B

Details of our findings re hepatitis B.

Peer-reviewed publication in preparation.

ACE Prevention: HIV

ACE Prevention: HIV

The project's findings and publications regarding HIV.

 Peer-reviewed publications in preparation

 

Pamphlet 8: HIV

 

ACE Prevention: Illicit drugs

ACE Prevention: Illicit drugs

Information regarding the project's findings and publications on illicit drugs.

 Tay-Teo K, Bulfone L, Carter R, Doran C, Hall W. Modelling the public health consequences of cannabis use in Australia. In preparation.

 
Tay-Teo K, Carter R, Doran C, Pirkis J, Hall W. Evaluating the economic value of the random roadside drug-testing program in Victoria, Australia. In preparation.
 
Tay-Teo K, Carter R, Doran C, Pirkis J, Hall W. The cost-effectiveness of the Gatehouse intervention. In preparation.
 
Tay-Teo K, Carter R, Doran C, Pirkis J, Hall W. The cost-effectiveness of CBT for drug dependency. In preparation.
 
 
 
 
 

Pamphlet 4: Cannabis

 

ACE Prevention: Indigenous results

ACE Prevention: Indigenous results

Findings and publications regarding Indigenous health.

 Ong K, Kelaher M, Anderson I, Carter R. A cost-based equity weight for use in the economic evaluation of primary health care interventions: case study of the Australian Indigenous population.International Journal for Equity in Health 2009, 8:34

 
Peer-reviewed publication on Indigenous Health Service Delivery (IHSD) template in preparation.
 
Peer-reviewed publication on hepatitis B/cirrhosis and liver cancer in preparation.
 
Briefing paper Blood pressure and cholesterol Indigenous (in progress)
 
Briefing paper Pre-diabetes (in progress)
 
 
 
Pamphlet Indigenous 3: Screening and early treatment of chronic kidney disease
ACE Prevention: Influenza

ACE Prevention: Influenza

The project's findings and publications regarding influenza.

ACE Prevention: Mental health

ACE Prevention: Mental health

Details of the project's findings on mental health.

Mihalopoulos C, Vos T, Pirkis J, Smit F, Carter R. The cost effectiveness of suicide prevention interventions. In preparation.
 
Mihalopoulos C, Vos T, Pirkis J, Smit F, Carter R. The cost-effectiveness of screening and treatment for the prevention of childhood/adolescent depression. In preparation.
 
Mihalopoulos C, Vos T, Pirkis J, Smit F, Carter R. The cost-effectiveness of prevention and treatment for post-natal depression. In preparation.
 
Mihalopoulos C, Vos T, Pirkis J, Smit F, Carter R. The cost-effectiveness of preventing psychosis. In preparation.
 
Mihalopoulos C, Vos T, Pirkis J, Carter R. The Economic Analysis of Prevention in Mental Health Programs. Annual Review of Clinical Psychology. 2011;7(1):169‐201.
 
Mihalopoulos C, Vos T, Pirkis J, Smit F, Carter R. The cost-effectiveness of screening and treatment for the prevention of childhood/adolescent anxiety. In preparation.
 
Mihalopoulos C, Vos T, Pirkis J, Smit F, Carter R. Does screening and treatment for the prevention of adult depression represent good value for money? Australian and New Zealand Journal of Psychiatry. 2010;epub ahead of print:1-9.
 
Briefing paper Childhood anxiety (ACE Steering Committee only; part of PhD work)
 
Briefing paper Childhood depression (ACE Steering Committee only; part of PhD work)
 
Briefing paper Youth psychosis (ACE Steering Committee only; part of PhD work)
 
Briefing paper Depression screening (ACE Steering Committee only; part of PhD work)
 
Briefing paper Post-partum depression (ACE Steering Committee only; part of PhD work)
 
Briefing paper Suicide prevention (ACE Steering Committee only; part of PhD work)
 
 
 
 
 
 

 

ACE Prevention: Multi component

ACE Prevention: Multi component

Findings and publications from this aspect of the project.

 Cobiac LJ, Vos T, Veerman JL. Cost-effectiveness of Weight Watchers and the Lighten Up to a Healthy Lifestyle program. Aust N Z J Public Health 2010;34(3):240–247.

ACE Prevention: Oral health

ACE Prevention: Oral health

The project's findings and publications around oral health.

ACE Prevention: Osteoarthritis

ACE Prevention: Osteoarthritis

The project's findings and publications on osteoarthritis.

ACE Prevention: Peptic ulcer disease

ACE Prevention: Peptic ulcer disease

This content is currently being prepared.

 Content to come

ACE Prevention: Physical activity

ACE Prevention: Physical activity

The project's findings and publications regarding physical activity.

ACE Prevention: Prediabetes

ACE Prevention: Prediabetes

Details of our findings re prediabetes.

ACE Prevention: Prostate cancer

ACE Prevention: Prostate cancer

Details of the project's findings regarding prostate cancer.

Peer-reviewed publication in preparation.
 

Pamphlet 5: Cervical cancer screening, SunSmart and PSA screening

 

ACE Prevention: Salt

ACE Prevention: Salt

This pages includes the project's findings regarding salt consumption.

Cobiac LJ, Vos T, Veerman JL. Cost-effectiveness of interventions to reduce dietary salt intake. Heart 2010;96:1920e1925. doi:10.1136/hrt.2010.199240
 

Pamphlet 15: Salt

 

ACE Prevention: Shingles

ACE Prevention: Shingles

The project's findings and publications regarding shingles.

ACE Prevention: Skin cancer

ACE Prevention: Skin cancer

Details of the project's findings regarding skin cancer.

Shih S, Carter R, Sinclair C, Mihalopoulos C, Vos T. Economic evaluation of skin cancer prevention in Australia. Preventive Medicine 2009;49:449–453.
 
 

 

ACE Prevention: Tobacco

ACE Prevention: Tobacco

This content is currently being prepared.

 Peer-reviewed publications in preparation.

 

Pamphlet 17: Tobacco - In preparation

ACE Prevention: Vision loss

ACE Prevention: Vision loss

Papers summarising our findings regarding vision loss.

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